PTH 1-34 (teriparatide) may not improve healing in proximal humerus fractures

Figures & data

Flow of patients through the study.

Table 1. Patient characteristics (all patients were women). 13 of 23 patients who underwent screening had osteoporosis

	PTH group n = 19	Control group n = 20
Mean age (range)	67 (54–82)	69 (54–94)
Fracture right/left	8/11	8/12
Diabetes	3	0
Osteoporosis	5/11	8/12

Table 2. Levels of pain at rest and during activity before the fracture, at 7 weeks, and at 3 months (VAS). There were no statistically significant differences between the groups (Mann-Whitney U-test)

	PTH group		Control group
	n	median (range)	n	median (range)	p-value
Before fracture
rest	19	0 (0–2)	20	0 (0–30)	0.5
activity		0 (0–13)		0 (0–70)	0.9
7 weeks
rest	19	1 (0–30)	20	9.5 (0–40)	0.4
activity		30 (0–71)		38.5 (0–71)	0.5
3 months
rest	19	0 (0–48)	19	0 (0–20)	0.7
activity		15 (0–63)		15 (0–70)	0.8