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RESEARCH COMMUNICATIONS

Role of ghrelin on testosterone secretion and the mRNA expression of androgen receptors in adult rat testis

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Pages 119-123 | Received 01 Jun 2010, Accepted 09 Aug 2010, Published online: 04 Jan 2011

Figures & data

Figure 1.  The effect of ghrelin on LH, FSH, and T. Serum concentrations of LH, FSH, and T in rats through intracerebroventricular administration with ghrelin. *indicates significant difference compared with the dosage of 0 nmol (P < 0.05).

Figure 1.  The effect of ghrelin on LH, FSH, and T. Serum concentrations of LH, FSH, and T in rats through intracerebroventricular administration with ghrelin. *indicates significant difference compared with the dosage of 0 nmol (P < 0.05).

Figure 2.  Effect of ghrelin on T secretion by cocultured Leydig cells.

Figure 2.  Effect of ghrelin on T secretion by cocultured Leydig cells.

Figure 3.  Histological observation of rat testis tissue by immunolocalization of GHS-R1a protein. (A) Testis: Leydig cells (arrow a), Sertoli cells (arrow b), primary spermatocytes (arrow c), secondary spermatocytes (arrow d), and spermatogonia (arrow e). (B) Testis: spermatids (arrow f). (C) negative control reaction carried out after substitution of PBS. A, B, C, Scale bar = 25 μm.

Figure 3.  Histological observation of rat testis tissue by immunolocalization of GHS-R1a protein. (A) Testis: Leydig cells (arrow a), Sertoli cells (arrow b), primary spermatocytes (arrow c), secondary spermatocytes (arrow d), and spermatogonia (arrow e). (B) Testis: spermatids (arrow f). (C) negative control reaction carried out after substitution of PBS. A, B, C, Scale bar = 25 μm.

Figure 4.  AR mRNA levels as a function of ghrelin. Expression of AR mRNA in the testis after injection of different dosages of ghrelin in rats. *significant differences between the control and injected group (P < 0.05).

Figure 4.  AR mRNA levels as a function of ghrelin. Expression of AR mRNA in the testis after injection of different dosages of ghrelin in rats. *significant differences between the control and injected group (P < 0.05).

Figure 5.  Effect of ghrelin on AR mRNA expression by cocultured Leydig cells.

Figure 5.  Effect of ghrelin on AR mRNA expression by cocultured Leydig cells.

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