Figures & data
Table 1. Ticagrelor and AR-C124910XX pharmacokinetic parameters after IV and oral administration.
Figure 1. (A) Ticagrelor and (B) AR-C124910XX plasma concentrations following a single oral dose of ticagrelor 90 mg and a 30 min IV infusion of ticagrelor 15 mg.
Figure 2. (A) Ticagrelor and (B) ARC124910XX plasma concentrations following a single dose of ticagrelor 100 mg as an oral suspension, immediate release tablet, and a suspension released into the proximal small bowel, distal small bowel, and ascending colon.
Table 2. Ticagrelor and AR-C124910XX pharmacokinetic parameters following dosing with ticagrelor 100 mg as various oral formulations.