ALSUntangled No. 26: Lunasin

Figures & data

Table I. M. McDuff's manual muscle testing scores (R/L), as evaluated by physical and occupational therapists who followed him. Numbers refer to Medical Research Council scale (ratings from 0 to 5, where 0 means no strength and 5 is normal).

	3/25/11	6/14/13	7/5/13	11/21/13	7/3/14
Shoulder Flexion	1/1		2−/2−		2−/2−
Shoulder Extension	1/1				2−/2−
Elbow Flexion	4/4		2−/2−		2−/2−
Elbow Extension	4/4		2−/2−		2−/2−
Wrist Flexion	4/4		0/0		2−/2−
Wrist Extension	4/4		0/0		2−/2−
Hip Flexion		2−/2−		2−/2−	3−/3−
Hip Extension		2−/2−		2−/2−	2/2
Knee Flexion		4−/4−		2−/2−	2+/2+
Knee Extension		4−/4−		2−/2−	4/4
Ankle Dorsiflexion		4−/4−		2−/2−	5/5
Ankle Plantar Flexion		4−/4−			2+/2+

Table II. Other cases of PALS reporting improvements on lunasin. These were obtained via e-mails. RN (Reliv Now), LX (Lunarich X), PV (Provantage). See text for details.

Age/Gender	Lunasin Dosing	Lunasin Duration (weeks)	Improvement Reported	Records To Confirm Diagnosis	Atypical Features	Records To Confirm Improvements
48/M	RN 3–4 scoops BID; LX 4 caps BID	6	Speech, swallowing, arm and leg strength, breathing	Y	Y (Pure Upper Motor Neuron Disease)	N
30/M	RN 3 scoops QD; LX 12 caps QD; PV 3 scoops QD	4	Improved handwriting, decreased twitching and cramps, easer to maintain weight	Y	N	N
76/M	RN 2–3 scoops QD; LX 6–7 caps QD	9	Stopped progressing; more alert	N	?	N
70/M	RN 1 scoop BID; LX 3 caps TID;	7	Improved energy, decreased spasms	N	?	N
59/F	RN 4.5 scoops QD, LX 12 caps QD; PV 9 Tablespoons QD	11	Improved hand, arm, torso strength; improved stiffness	N	?	N
64/M	Classic 2 scoops QD, LRX 12 caps QD	11	Improved walking and energy	N	?	N
43/M	LRX 9 caps QD	4	None	N	?	N
63/F	LRX 9 caps QD	8	Improved speech, limb strength, fluidity and energy	N	Pure Upper Motor Neuron	N
66/M	?	4	None	N	?	N
74/M	RN ½ scoops QD; LRX 2 caps QD; PV 1.2 scoop QD.	8	None	N	?	N
?/M	RN 3 scoops QD; LRX 12 caps QD; PV 3 scoops QD	8	Improved speech	N	?	N
49/F	?	8	Improved breathing, twitching	N	?	N
74/?	?	8	Improved walking	N	Pure lower motor neuron disease	N
51/M	?	8	None	N	?	N
55/M	?	8	Improved swallowing, leg strength, energy	N	?	N
?/M	?	8	Improved sleep	N	?	N
?/F	?	8
?/F	RN 1 scoop QD; LRX 5 capsules QD, PV 1 scoop QD, others	11	Improved arm and leg strength	N	?	N