Figures & data
Figure 1. (A) Preparation of a triblock copolymer of PLGA-PEG, and (B) mechanism of PLGA-PEG prepared by Sn (Oct)2 as catalyst. PEG, poly (ethylene glycol); PLGA, poly (D, L-lactic-co-glycolic acid).
Figure 2. FT-IR diagram of PLGA-PEG.
Figure 3. FT-IR diagram of curcumin-loaded PLGA-PEG.
Figure 4. 1H NMR spectrum of PEG-PLGA co-polymer.
Figure 5. Scanning electron microscopy of PLGA-PEG.
Figure 6. Scanning electron microscopy of curcumin-loaded PLGA-PEG.
Figure 7. Curcumin release for different pHs and temperatures.
Figure 8. MTT assay results for 24h. Cytotoxic effects of different concentrations of free curcumin and curcumin-loaded PLG-PEG in the MCF-7 human breast cancer cell line.
Figure 9. MTT assay results for 48h. Cytotoxic effects of different concentrations of free curcumin and curcumin-loaded PLG-PEG in the MCF-7 human breast cancer cell line.
Figure 10. MTT assay results for 72h. Cytotoxic effects of different concentrations of free curcumin and curcumin-loaded PLG-PEG in the MCF-7 human breast cancer cell line.
Table I. IC50 values of curcumin and curcumin-loaded PLGA-PEG at different times of incubation.