Figures & data
Table I. Description of immunization protocol.
Figure 1. TEM images of ISCOMs containing Quil A.
Figure 2. % cell viability of Plain Quil A, Iscomatrix and ISCOMs formulations.
Figure 3. Comparative hemolytic profiles.
Figure 4. IgG titer after 14, 28 and 42 days following pulmonary immunization. Statistical analysis was carried out by two-way analysis of variance followed by post-hoc Bonferroni post-tests comparing all vs. control. Data compared with plain antigen as control. ‘*’ denotes P < 0.05, considered as significant, ‘**’ denotes P < 0.01 and ‘***’ denotes P < 0.001.
Figure 5. IgA titer at 42 days after pulmonary immunization.
Figure 6. IgM titer after 14, 28 and 42 days following pulmonary immunization. Statistical analysis was carried out by two-way analysis of variance followed by post-hoc Bonferroni post-tests comparing all data vs. control. Data compared with plain antigen as control. ‘*’ denotes P < 0.05, considered as significant, ‘**’ denotes P < 0.01 and ‘***’ denotes P < 0.001.
Figure 7. IgG1 titer after 14, 28 and 42 days following pulmonary immunization. Statistical analysis was carried out by two-way analysis of variance followed by post-hoc Bonferroni post-tests comparing all data vs. control. Data compared with plain antigen as control. ‘*’ denotes P < 0.05, considered as significant, ‘**’ denotes P < 0.01 and ‘***’ denotes P < 0.001.
Figure 8. IgG2a titer after 14, 28 and 42 days following pulmonary immunization. Statistical analysis was carried out by two-way analysis of variance followed by post-hoc Bonferroni post-tests comparing all data vs. control. Data compared with plain antigen as control. ‘*’ denotes P < 0.05, considered as significant, ‘**’ denotes P < 0.01 and ‘***’ denotes P < 0.001.
