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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 44, 2016 - Issue 3
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ORIGINAL ARTICLE

Preparation and characterization of gatifloxacin-loaded alginate/poly (vinyl alcohol) electrospun nanofibers

Saravanakumar ArthanariDepartment of Chemical Engineering, Hanseo University, Chungcheongnam-Do, South Korea
,
Ganesh ManiDepartment of Chemical Engineering, Hanseo University, Chungcheongnam-Do, South Korea
,
Jun Ho JangSeoryeong High School, Chungcheongnam-Do, South Korea
,
Je O ChoiSeoryeong High School, Chungcheongnam-Do, South Korea
,
Yun Ho ChoSeoryeong High School, Chungcheongnam-Do, South Korea
,
Jung Ho LeeGarak High School, Seoul, South Korea
,
Seung Eun ChaHanseo Regional Innovation Center, Hanseo University, Chungcheongnam-Do, South Korea;Department of Business Administration, Sungkyunkwan University, Seoul, South Korea
,
Han Seok OhDepartment of Chemical Engineering, Hanseo University, Chungcheongnam-Do, South Korea
,
Deok Han KwonSeoryeong High School, Chungcheongnam-Do, South Korea
&
Hyun Tae JangDepartment of Chemical Engineering, Hanseo University, Chungcheongnam-Do, South Korea;Hanseo Regional Innovation Center, Hanseo University, Chungcheongnam-Do, South KoreaCorrespondence[email protected]
 show all
Pages 847-852 | Received 29 Sep 2014, Accepted 07 Nov 2014, Published online: 15 Dec 2014

Figures & data

Figure 1. SEM micrograph of (A) 3/7, (B) 2/8, (C) 1/9 plain SA–PVA nanofibers, and (D) gatifloxacin-loaded PVA–SA nanofibers.

Figure 1. SEM micrograph of (A) 3/7, (B) 2/8, (C) 1/9 plain SA–PVA nanofibers, and (D) gatifloxacin-loaded PVA–SA nanofibers.

Figure 2. FTIR spectra of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug loaded PVA–SA nanofibers.

Figure 2. FTIR spectra of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug loaded PVA–SA nanofibers.

Figure 3. TGA of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug-loaded PVA–SA nanofibers.

Figure 3. TGA of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug-loaded PVA–SA nanofibers.

Figure 4. XRD of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug-loaded PVA–SA nanofibers.

Figure 4. XRD of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug-loaded PVA–SA nanofibers.

Figure 5. DSC pattern of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug-loaded PVA–SA nanofibers.

Figure 5. DSC pattern of (i) gatifloxacin, (ii) PVA–SA composite nanofibers, and (iii) drug-loaded PVA–SA nanofibers.

Figure 6. Degree of swelling of PVA–SA composite nanofibers and drug-loaded PVA–SA nanofibers.

Figure 6. Degree of swelling of PVA–SA composite nanofibers and drug-loaded PVA–SA nanofibers.

Figure 7. Drug release pattern of drug-loaded PVA–SA nanofibers.

Figure 7. Drug release pattern of drug-loaded PVA–SA nanofibers.

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