Biomedical and biological applications of quantum dots

Figures & data

Figure 1. Properties of QDs. QDs are characterized by broad absorption spectra, are composition-tunable, size- tunable, and show slight fluorescence.

Figure 2. One more approach includes wrapping the hydrophobic surface groups with block copolymers or phospholipid micelles.

Figure 3. Schematic examples for some bio-applications of QDs (Tilley et al. 2005, Warner et al. 2005).

Table

Size (nm)	Emission peak (nm)	Color
2.2	495	Blue
2.9	550	Green
3.1	576	Yellow
4.1	595	Orange
4.4	611	Orange
4.8	644	Red
7.3	655	Dark Red

Figure 4. Schematic representation of the encapsulation procedure of QD-BRET probes (Hoshino et al. 2008).

Figure 5. Quantum dots could be used to stimulate damaged cells in the brain and eye, for treating a range of conditions (Lakowicz 1999).

Tilley RD, Warner JH, Yamamoto K, Matsui I, Fujimori H. 2005. Chem. Comm. 1833–1835.

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Warner JH, Hoshino A, Yamamoto K, Tilley RD. 2005. Angew Chem Int Ed. 44:4550–4554.

 PubMed Web of Science ®Google Scholar

Hoshino A, Manabe N, Fujioka K, Hanada S, Yasuhara M, Kondo A, Yamamoto K. 2008. GFP expression by intracellular gene delivery of GFP-coding fragments using nanocrystal quantum dots. Nanotechnology.

 Web of Science ®Google Scholar

Lakowicz JR. 1999. Principles of Fluorescence Spectroscopy. Kluwer Academic/Plenum Publishers.

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