Figures & data
Figure 1. Schematic representation of the mechanism of formation of nanosuspensions by the antisolvent precipitation technique.
Figure 2. Optimization of drug concentration with respect to particle size and PDI.
Figure 3. Optimization of the concentration of poloxamer and soya lecithin.
Figure 4. Optimization of the time duration of ultrasonication.
Figure 5. Optimization of the solvent/-antisolvent ratio.
Figure 6. SEM image of efavirenz freeze- dried nanosuspensions.
Figure 7. X-ray diffraction pattern of pure drug.
Figure 8. X-ray diffraction pattern of lyophilized nanosuspensions.
Figure 9. Saturation solubility of plain drug and freeze- dried drug nanosuspensions.
Figure 10. In- vitro drug release profile of drug crystals and nanosuspensions.
