Analysis of the in vitro nanoparticle–cell interactions via a smoothing-splines mixed-effects model

Figures & data

Table I. Nanoparticle characteristics.

Variable name	Value
Type of NPs	Silica, PMMA, PLA
Diameter of NPs (Size)	50 nm and 100 nm for silica and PMMA 250 nm for PLA
Surface charge of NPs (Charge)	Positive (+) and negative (−)
Density of NPs (Density)	0.001 mg/l and 0.01 mg/l
Incubation time (Time)	0, 3, 6, 12, 24, 36, 48 h for silica, PMMA and PLA
	0, 1.5, 4, 9, 18, 30, 42 h for silica

Figure 1. Silica 50 nm predictions.

Figure 2. Silica 100 nm predictions.

Figure 3. PMMA 50 nm predictions.

Figure 4. PMMA 100 nm predictions.

Figure 5. PLA predictions.