Magnetic nanoparticles in cancer diagnosis and treatment: a review

Figures & data

Figure 1. The role of magnetic drug targeting. Nanoparticles-based magnetic iron oxide are functionalized with a chemotherapeutic agent and injected directly into the arterial supply of the tumor (Dürr et al. 2013, Namiki et al. 2009)

Figure 2. Multiple applications of nanoparticles in the diagnosis and treatment of different types of cancer (Colombo et al. 2012)

Figure 3. Scheme of the treatment strategy using magnetic nanoparticles (MNPs). Functionalized MNPs accumulate in the tumor tissues by the drug delivery system (DDS) (Sun et al. 2008)

Figure 4. Scheme image of a magnetic drug delivery system

Table1. Table of specific absorption rate (SAR) values and parameters of nanoparticles

References	Material	Diameter (nm)	F (kHz)	H (kA m^−1)	f × H (10^9 Hz A m^−1)	f × H^2 (10^12 A^2 m^−2 s^−1)	SARMNP (10^3 W kg^−1)	ILP (10^−12 W m^2 s A^−2 kg^−1)
Jiang et al. (2013)	Fe3O4	9	500	37.3	18.7	695.6	152	219
This work	Fe3O4	5	523	10	5.2	52.3	20	382
Jiang et al. (2013)	Fe3O4	15	500	37.3	18.7	695.6	333	479
Jiang et al. (2013)	Fe3O4	12	500	37.3	18.7	695.6	349	502
Cervadoro et al. (2013)	Fe3O4	8	100	23.9	2.4	57.1	52.8	924
Cervadoro et al. (2013)	Fe3O4	8	100	9.6	1.0	9.2	17.2	1866
Akbarzadeh et al. (2012a)	Fe3O4	12.5	600	3.2	1.9	6.1	21.98	3577
Akbarzadeh et al. (2012b)	Fe3O4	15.7	600	3.2	1.9	6.1	28.32	4609

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