Transplantation of umbilical cord and bone marrow-derived mesenchymal stem cells in a patient with relapsing-remitting multiple sclerosis

Figures & data

Figure 1. Axial (A–E) fluid attenuation inversion recovery (FLAIR) MRI Brain and sagittal T2-weighted MRI of the cervical cord (1–5) demonstrate a stable distribution of lesions from 2007 (A and 1) to 2012 (F and 6).

Table 1. Summary of MSC treatment, adverse events and clinical disability score (EDSS)

	Date	Source MSC	Route	Dose	Adverse events	EDSS
Pre-treatment	6/9/2006	-	-	-	-	3.0
1	26/11/2008	BM	iv	1.32x10^7	Nil	3.5
		BM	it	6.3x10^5	Nil
2	19/02/2009	BM	iv	6.0x10^7	Nil
		BM	it	1.4x10^7	Nil
3	7/05/2009	BM	iv	8.9x10^7	Nil	2.5
4	4/08/2009	UC	iv	1.2x10^8	Dizziness, headache
5	8/01/2010	BM	it	1.47x10^5	Nil	2.5
6	29/08/2010	UC	iv	3.27x10^8	Rash, Fever
7	22/04/2011	UC	iv	1.4x10^8	Dizziness, Headache
8	29/12/2011	UC	iv	1.54x10^8	Headache	2.0
Post-treatment	12/07/12	-	-	-	-	2.0