Figures & data
Figure 1. Schematic outline of the formation of liposomes. Lipid molecules, when dispersed in an aqueous phase form bilayers vesicles which can be prepared in a range of sizes from larger multilamellar vesicles, through to small unilamellar vesicles.
Figure 2. Summary of the advantages and disadvantages of some of the common processes used in the manufacture of liposomes.
Figure 3. Schematic outline of the principles involved in the preparation of liposomes using microfluidics.
Figure 4. Liposomal adjuvants can be prepared from a range of lipids, for example the cationic lipid Dimethyldioctadecylammonium bromide and D-(+)- trehalose 6,6’-dibehenate. Combined together, these lipids from liposomes with strong adjuvant properties.
Figure 5. Formulation parameters shown to impact on the formation of a DDA:TDB liposome depot at the injection site and a summary of the impact this has on immune responses.
