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Acta Oto-Laryngologica Volume 128, 2008 - Issue 3
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ORIGINAL ARTICLE

Susceptibility to impulse noise trauma in different species: guinea pig, rat and mouse

Maoli Duan Center for Hearing and Communication Research, Stockholm, Sweden; Department of Otolaryngology, Karolinska Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden; Department of Otolaryngology, Affiliated Hospital of Anhui Medical University, Örebro, SwedenCorrespondence[email protected]
, PhD , MD,
Göran Laurell Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden; Department of Clinical Sciences, Umeå University, Umeå, Sweden
,
Jianxin Qiu Center for Hearing and Communication Research, Stockholm, Sweden; Department of Otolaryngology, Karolinska Hospital, Stockholm, Sweden; Department of Otolaryngology, Affiliated Hospital of Anhui Medical University, Örebro, Sweden
&
Erik Borg Ahlsen Research Institute, Örebro University Hospital, Örebro, Sweden
Pages 277-283 | Received 20 Feb 2007, Published online: 08 Jul 2009
 
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Abstract

Conclusion. The results indicate that susceptibility to impulse noise differs in the three species. Objective. To test the hypothesis that there is different susceptibility to impulse noise trauma in three species: the guinea pig, rat and mouse. Materials and methods. Three groups of animals were exposed to the same impulse noise and the effect on cochlear pathology was examined using auditory brainstem response thresholds. Results. It was found that the rat and mouse are more sensitive to impulse noise than the guinea pig.

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