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Scandinavian Journal of Infectious Diseases Volume 39, 2007 - Issue 6-7
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CASE REPORT

Isolated CNS Whipple disease: Acute onset and relapsing-remitting course

Dr Julián Benito-León From the Department of Neurology, Móstoles General Hospital, Móstoles, Madrid, SpainCorrespondence[email protected]
,
Javier Arpa Department of Neurology, University Hospital ‘La Paz’, Madrid, Spain
,
Elan D. Louis G.H. Sergievsky Center, Department of Neurology, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA
,
Inmaculada Herrera Department of Microbiology, National Centre of Microbiology, National Institute of Health Carlos III, Madrid, Spain
&
Asia De La Loma Department of Microbiology, National Centre of Microbiology, National Institute of Health Carlos III, Madrid, Spain
Pages 623-625 | Received 08 Nov 2006, Published online: 08 Jul 2009
 
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Abstract

Isolated CNS Whipple disease (WD) carries a poor prognosis, particularly if untreated. We describe 2 patients with isolated CNS WD who presented unusually with an acute onset followed by a relapsing-remitting course. Neither was diagnosed with WD until they had had several relapses.

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