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Spectroscopy Letters
An International Journal for Rapid Communication
Volume 51, 2018 - Issue 4
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Original Articles

Humic-based bionanocomposites containing stable paramagnetic gold nanoparticles for prospective use in pharmaceuticals

Spartak S. KhutsishviliA.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, RussiaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-6224-5968View further author information
ORCID Icon,
Marina V. LesnichayaA.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, RussiaView further author information
,
Tamara I. Vakul’skayaA.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, RussiaView further author information
,
Gania DolmaaChemistry and Chemical Technology Institute of the Mongolian Academy of Sciences, Ulaanbaatar, MongoliaView further author information
,
Galina P. AleksandrovaA.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, RussiaView further author information
,
Aleksandr L. RakevichIrkutsk Branch of the Institute of Laser Physics of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, RussiaView further author information
&
Boris G. SukhovA.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, RussiaView further author information
 show all
Pages 169-173 | Received 08 Nov 2017, Accepted 14 Feb 2018, Published online: 15 Mar 2018
 
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ABSTRACT

Structural peculiarities and supramolecular organization of medicinally promising nanocomposites, synthesized from humic substances, which essentially differ depending on decomposition degree, have been studied using electron spin resonance, transmission electron, and confocal laser scanning microscopy techniques and some other modern physical–chemical methods. It is shown that stable zero-valent gold nanoparticle of about 10–17 nm in size are formed in a natural macromolecular matrix. The nanocomposites obtained turn out to be stable in aggregative state for a long time and preserve their properties that are extremely important for prospective medicinal substances.

Acknowledgment

The authors are grateful to the Baikal Analytical Center for the special measurements.

Additional information

Funding

This work was supported by the President Grant of Russian Federation (Grant MK-7149.2016.3).

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