Microwave‐Assisted Construction of Diaryl Ethers Directly from Arylmethanesulfonates as Convenient Latent Phenols with Aryl Halides

Abstract

The microwave‐assisted synthesis of diaryl ethers directly from aryl halides and arylmethanesulfonates, which as latent phenols obviate a deprotection step prior to the S_NAr reaction, in the presence of Cs₂CO₃ is described. The reaction time was very short (6–9 min), and good to excellent yields (53–90%) with the wide substrate scope were achieved without any catalyst.

Keywords:

• aryl halides
• arylmethanesulfonates
• diaryl ethers
• microwave
• S_NAr reaction

Acknowledgment

This study was supported by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry (No. 14110101). We also thank Northwest A&F University for the financial support from the Program for Excellent Talents.