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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2007 - Issue 1
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Original Articles

Synthesis of 1,8‐Naphthyridine‐4(1H)‐one Sulfonamides by Thermolysis of 2‐Aminopyridinemethylene (Meldrum's Acid) Derivative

Luiz Everson da Silva Department of Chemistry, Federal University of Mato Grosso State (UFMT), Cuiabá, MT, BrazilCorrespondenceluiz_everson@yahoo
,
Antonio Carlos Joussef Department of Chemistry, Federal University of Santa Catarina State (UFSC), Florianópolis SC, Brazil
,
Ricardo José Nunes Department of Chemistry, Federal University of Santa Catarina State (UFSC), Florianópolis SC, Brazil
&
Kely Navakoski de Oliveira Department of Chemistry, Federal University of Santa Catarina State (UFSC), Florianópolis SC, Brazil
Pages 15-20 | Received 01 Jun 2007, Published online: 25 Jan 2008
 
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Abstract

An efficient synthesis of 1,8‐naphthyridine‐4(1H)‐one sulfonamide derivatives by thermolysis of 2‐pyridylaminomethylene (Meldrum's acid derivative) starting from 4,6‐dimethyl‐2‐aminopyridine (1) is described.

Acknowledgment

The authors are indebted to Capes (Brazil) and Brazilian Research Council (CNPq) for financial support of this work.

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