Diethylamine-Catalyzed Dimerization of Thiols: An Inexpensive and Green Method for the Synthesis of Homodisulfides Under Aqueous Conditions

Abstract

Under H₂O / Et₂NH / atmospheric oxygen conditions, thiols are converted to their respective homodisulfides within a few hours. The process is conducted at room temperature for quantitative dimerization of aromatic, benzylic, and aliphatic thiols without the use of any extra additive.

Keywords:

• Aqueous conditions
• disulfides
• oxidation
• thiols

ACKNOWLEDGMENT

The Ministry of Science, Research, and Technology of Iran is gratefully acknowledged for partial financial support of this work.

Notes

^a GC yields.

^b Under O₂ bubbling conditions.

^a Isolated yields.

^a This work.