Synthetic Access to New Carbamate and Thiocarbamate Derivatives from Pyridinecarbaldehyde Oximes and Hydroxypyridines

Abstract

The synthesis of pyridine carbamate and thiocarbamate derivates is described. A series of oxime carbamate and thiocarbamate derivatives were synthesized by the addition of 2-, 3-, and 4-pyridinecarbaldehyde oximes to isocyanates and isothiocyanates. Furthermore, carbamate and thiocarbamate derivatives of pyridine were synthesized by the addition of 2-, 3-, and 4-hydroxy pyridine to isocyanates and isothiocyanates. Their structures were confirmed by both analytical and spectral data.

Keywords:

• Addition
• carbamate
• carbamoyl oxime
• thiocarbamate

ACKNOWLEDGMENT

We thank the Research Foundation of Selcuk University (SUBAP, Grant No. 07201010) for financial support of this work.

Notes

^a Lit. 132 °C ^{[ 23 ]}.