Abstract
One-pot, three-component condensation of benzil/benzoin, substituted aromatic aldehydes, and ammonium acetate in an ethanol–water (1:1, v/v) solvent system using sulfated tin oxide catalyst under reflux condition afforded corresponding 2,4,5-triaryl-1H-imidazoles in excellent yield. The remarkable advantages offered by this method include green and reusable catalyst, mild reaction conditions, fast reaction rate, and excellent yield of products. This novel methodology maintains atom economy and an environmentally friendly approach.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
The authors are thankful to Dr. P. L. More, Dnyanopasak College, Parbhani, for the encouragement during this research.
Notes
a Yield of isolated products.
a Yield of isolated products.
a Reaction conditions: 4-hydroxy benzalaldehyde (12 mmol), benzil (10 mmol), ammonium acetate (40 mmol), and sulfated tin oxide (10 mol%).
b Yield of isolated products.