Abstract
A simple and efficient tetrahydropyranylation of alcohols and phenols has been developed using NaHSO4-SiO2 (0.5 mol%) as a catalyst under solvent-free conditions to yield corresponding tetrahydropyranyl ethers in excellent yields.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENTS
Research funds of the University of Johannesburg and the Research Center for Synthesis and Catalysis are gratefully acknowledged. We also thank Dr. Gareth Arnott for proofreading our manuscript.
Notes
a Isolated yields.
a Isolated yields.
b slightly low yields are as a result of the high volatility of the product.
c To dissolve the solid alcohols, 2.5 equivalence of DHP was used.