Abstract
A simple and efficient synthesis of ammonium 3,5-dicyano-4-aryl-2,6-pyridinedionates was accomplished via one-pot, three-component reaction of aromatic aldehydes, amines, and cyanoacetamide. This unprecedented methodology had some potential advantages such as the common available starting material, short reaction time, good yield, broad substrate scope, and convenient operation.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENTS
This work was financially supported by the National Natural Science Foundation of China (Grant No. 20972132) and the Key Laboratory of Environmental Resource and Material, Jiangsu Province.