Facile Synthesis of 1,3,5-Triaroylbenzenes by Direct Cyclotrimerization of Ketone Enolates

Abstract

Based on the improvement of the synthesis of 1,3,5-triaroylbenzenes, a convenient acid catalytic strategy was carried out and a series of 1,3,5-triaroylbenzenes were synthesized. The reaction temperature effect was investigated, and a mechanism of the cyclotrimerization has been proposed.

GRAPHICAL ABSTRACT

Keywords:

• Acid
• cyclotrimerization
• ketone enolate
• 1,3,5-triaroylbenzene

ACKNOWLEDGMENTS

We acknowledge the National Natural Science Foundation of China (No. 21004014) and the Foundation for Distinguished Young Talents in Higher Education of Guangdong (No. LYM10091) for financial support.