Abstract
Direct metal-free alkenylation of 2-methylindole via acid-mediated Michael addition–elimination reaction with ethoxymethylenemalononitrile or ethyl ethoxymethylenecyanoacetate affords 3-indolyl-2-cyanoacrylonitrile and ethyl 3-indolyl-2-cyanoacrylate. Behavior of 1H-indole is predictably different.
ACKNOWLEDGMENT
We gratefully acknowledge partial financial support from Alzahra University Research Council.