Abstract
In this work, polymer-supported copper(I) iodide catalyst and macroporous polymer-supported azide reagent were used to simplify the synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from α-bromo ketones/amides/esters following green chemistry principles. This new one-pot protocol facilitates the workup of the reaction and provides the products in short times and excellent yields. Heterogeneous catalyst and reagent can be reused at least for five runs without significant yield decreases.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
We are grateful to the Research Council of Islamic Azad University, Gachsaran Branch, for financial support.
Notes
a Yields refer to isolated and pure products.
a Yields refer to pure and separated products.
a Yields refer to isolated and pure products.