Multicomponent Reaction for Synthesis of N-Arylsulfonyl Pyrazoles

Abstract

A synthesis of functionalized N-arylsulfonyl pyrazoles from the multicomponent reaction of arylsulfonyl hydrazones and dialkyl acetylenedicarboxylates in the presence nucleophilic compounds such as pyridine, isoquinoline, or triphenylphosphine, in good yields, is described.

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GRAPHICAL ABSTRACT

Keywords:

• Arylsulfonyl hydrazone
• dialkyl acetylenedicarboxylate
• N-arylsulfonyl pyrazole
• nucleophile