Abstract
Substituted 1H-benzimidazoles, pyrazolones, and pyrazoles have been synthesized by the condensation of ortho-phenylenediamines and phenylhydrazines, respectively, with ethyl 4-chloro-3-oxobutanoate in good yields. The present approach is novel, straightforward, and being reported for the first time with ethyl 4-chloro-3-oxobutanoate.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENTS
The authors thank M. Lakshmi Kantam, Director, and S. Chandrasekhar, Head, Natural Products Chemistry Division, Council of Scientific and Industrial Relations–Indian Institute of Chemical Technology (CSIR-IICT), for their constant encouragement.
SUPPLEMENTARY MATERIAL
Spectral data for the synthesized compounds can be accessed on the publisher’s website.