(±)-Camphor-10-sulfonic acid as recyclable and efficient catalyst for the synthesis of some novel coumarin derivatives

ABSTRACT

A highly competent-diversity oriented synthesis of coumarin core derivatives using a Knoevenagel condensation followed by Michael addition and subsequent cyclization in the presence of (±)-camphor-10-sulfonic acid in a water/ethanol (1:1) solvent system is depicted. Furthermore, easy workup procedures with good yield, rapid reactions with high atom economy, and catalyst recyclability are the fascinating features of the procedure.

GRAPHICAL ABSTRACT

KEYWORDS:

• (±)-Camphor-10-sulfonic acid
• cyclic 1,3-diketone
• diversity-oriented multicomponent reactions
• substituted 3-formylchromone