Synthesis of symmetrical terphenyl derivatives by PdCl₂-catalyzed Suzuki–Miyaura reaction of dibromobenzene using 3-(diphenylphosphino)propanoic acid as a ligand

ABSTRACT

A simple and efficient catalytic system for PdCl₂ catalyzing the Suzuki–Miyaura reaction of dibromobenzene and arylboronic acid has been developed by using 3-(diphenylphosphino)propanoic acid as a ligand in dimethylsulfoxide at 100 °C. Using this method, a series of symmetrical terphenyl derivatives were obtained with remarkably good yields, up to 93%.

GRAPHICAL ABSTRACT

KEYWORDS:

• Catalysis
• palladium
• P,O ligand
• Suzuki–Miyaura reaction
• synthesis
• terphenyls