Cobalt mediated by desulfurization toward the synthesis of isothiocyanates

ABSTRACT

A highly efficient and simple protocol for the construction of aromatic and aliphatic isothiocyanates from their respective amines in the presence of cheap, readily available, and air-stable cobalt catalyst is described. All reactions were carried out under optimized reaction conditions and gave target products in good to excellent yields within shorter reaction time.

GRAPHICAL ABSTRACT

KEYWORDS:

• C-N bond formation
• cobalt catalyst
• desulfurization
• isothiocyanates
• room temperature

Acknowledgments

The authors are thankful to the Department of Chemistry, Bapatla Engineering College, Bapatla, for providing work space and to Icon Pharmaceutical Laboratory for providing instrumental support.