Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 54, 2024 - Issue 7
Submit an article Journal homepage
92
Views
0
CrossRef citations to date
0
Altmetric
Articles

A facile, regio and diastereoselective synthesis of functionalized azetidin-2-ones: Cu(I) mediated Kinugasa reaction of functionalized nitrones with acetylenic alcohols

Priyanka Sharmaa Department of Chemistry, I. K. Gujral Punjab Technical University, Kapurthala, Punjab, IndiaView further author information
,
Dinesh Mahajanb Translational Health Science and Technology Institute, Faridabad, Haryana, IndiaView further author information
,
Vipan Kumarc Department of Chemistry, Guru Nanak Dev University, Amritsar, Punjab, IndiaView further author information
,
Rupesh Kumara Department of Chemistry, I. K. Gujral Punjab Technical University, Kapurthala, Punjab, IndiaView further author information
&
Gaurav Bhargavaa Department of Chemistry, I. K. Gujral Punjab Technical University, Kapurthala, Punjab, IndiaCorrespondence[email protected] [email protected]
View further author information
Pages 583-591 | Received 21 Nov 2023, Published online: 26 Feb 2024
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

The manuscript presents an efficient method for the synthesis of various cis-azetidin-2-ones with high regio- and diastereoselectivity. This approach utilizes Kinugasa reaction involving diverse functionalized nitrones, including diaryl nitrones and α,β-unsaturated nitrones, in conjunction with acetylenic alcohols. Copper (I) serves as a catalyst to facilitate the transformation.

Graphical Abstract

Acknowledgment

I. K. Gujral Punjab Technical University (PTU), Kapurthala is acknowledged for providing research facilities.

Conflict of interest

Authors declare no conflicts of interest.

Additional information

Funding

The financial support from Department of Science and Technology (DST), New Delhi, under Scheme No: SB/FT/CS-079/2012 is highly acknowledged.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 422.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.