An overall development on catalytic applications of potassium phthalimide (PPI) and potassium phthalimide-N-oxyl (POPINO) in organic synthesis

Abstract

Potassium phthalimide (PPI) and Potassium phthalimide-N-oxyl (POPINO) have emerged as a versatile and efficient catalyst in various organic synthesis reactions, playing a crucial role in the development of sustainable and environmentally friendly synthetic methodologies. This review highlights the catalytic applications of PPI and POPINO in diverse transformations, showcasing its potential as a valuable tool in modern organic synthesis. The multifaceted reactivity of PPI and POPINO has been explored in reactions such as nucleophilic substitutions, condensations, cycloadditions, and oxidation processes, making it an attractive catalyst for the synthesis of complex organic molecules.

GRAPHICAL ABSTRACT

Keywords:

• Catalysis
• multicomponent reactions (MCRs)
• one-pot synthesis
• green synthesis
• organocatalyst
• potassium phthalimide (PPI)
• potassium phthalimide-N-oxyl (POPINO)
• recycled
• reusable

Acknowledgements

The authors are thankful to the Department of Chemistry, Monark University, Hasmukh Goswami College of Engineering AT, Vahelal-Dahegam Road, Naroda, Ahmedabad, Gujarat, for providing the necessary facilities.

Disclosure statement

No potential conflict of interest was reported by the author(s).