Highly Efficient Practical Procedure for the Synthesis of Azine Derivatives Under Solvent-Free Conditions

Abstract

A general and useful method for the synthesis of azines of aromatic aldehydes and ketones in good yields was elaborated. This reaction is carried out under solvent-free conditions and in the absence of catalyst to afford good yields of the relevant azines. The reaction is also environmentally friendly without the inconvenience of undesired by-products and has advantages over the previously reported methods. Products were characterized by the usual procedures (infrared, ¹H NMR, and ¹³C NMR).

Keywords:

• Azine
• carbonyl compound
• environmentally friendly
• solvent-free

ACKNOWLEDGMENT

The authors thank the Department of Organic Chemistry, University of Kashan, for financial support of this work.

Notes

^a Yields refer to the pure isolated products.