Synthesis of 2-Arylbenzimidazoles in Water

Abstract

A simple and efficient procedure for the synthesis of 2-arylbenzimidazoles through a one-pot condensation of o-phenylenediamines with aryl aldehydes in water is described. Short reaction time, large-scale synthesis, easy and quick isolation of the product, and excellent yield are the main advantages of this procedure.

Keywords:

• Benzimidazoles
• excellent yields
• green chemistry
• o-phenylenediamine

ACKNOWLEDGMENT

The authors gratefully acknowledge financial support from the University Grant Commission, New Delhi.

Notes

^a Isolated product.

^b Resulting 2-arylbenzimidazole.

^a Reaction time 2 h.

^b Isolated product.