Abstract
The U.S. Army and U. S. Army Public Health Center are dedicated to protecting the health, and readiness of Department of the Army Service Members, civilians, and contractors. Despite implementation of health programs, policies and tobacco control interventions, the advent of electronic nicotine delivery systems (ENDS), including electronic cigarettes (e-cigs), represent unregulated and poorly defined systems to supplant or substitute use of conventional nicotine products (e.g., cigarettes and pipe tobacco). E-cigs present unique challenges to healthcare officials vested in preventive medicine. The health impact of an e-cig and vaping on an individual’s acute or chronic disease susceptibility, performance and wellness, is fraught with uncertainty. Given the relatively recent emergence of e-cigs, high-quality epidemiological studies, and applied biological research studies are severely lacking. In sparsely available epidemiological studies of short-term cardiovascular and respiratory health outcomes, any attempt at addressing the etiology of acute and chronic health conditions from e-cig use faces incredible challenges. Until relatively recently, this was complicated by an absent national regulatory framework and health agency guidance on the manufacture, distribution, selling and use of e-cigs or similar ENDS devices and their chemical constituents. Two key issues underpin public health concern from e-cig use: 1) continued or emergent nicotine addiction and potential use of these devices for vaping controlled substances; and 2) inadvertent sudden-onset or chronic health effects from inhalational exposure to low levels of complex chemical toxicants from e-cig use and vaping the liquid. Herein, the health impacts from e-cig vaping and research supporting such effects are discussed.
Acknowledgements
Authors express their sincere thanks and gratitude to both Dr. Desmond I. Bannon (Health Effects Division, Directorate of Toxicology, APHC), and Dr. Mark S. Johnson (Director of Toxicology, APHC), and Ms. Debra C. Colbeck (Health Risk Communication, APHC), for their careful and critical review of this comprehensive manuscript. All authors have reviewed and approve of the content found in this article.
Disclosure statement
Authors declare that no personal, financial or material conflict of interest, in whole or in part, exists in regard the drafting, authorship, scientific content or submission of this comprehensive review article for publication.
Disclaimer
This article was prepared for unrestricted and unlimited public educational use only. The views and assertions expressed in this article are the private views of the authors and do not necessarily reflect, nor should they be construed as reflecting the views, and official policy of the Department of Defense, the Department of the Army, the U.S. Army Medical Department or the U.S. Federal Government. Further, use of trademarked name(s) does not imply endorsement by the U.S. Army but is intended only to assist in identification of a specific product.