Acute Posterior Multifocal Placoid Pigment Epitheliopathy After Cerebral Sinus Thrombosis

Abstract

A 19-year old woman presenting with headaches, focal neurological deficits, and seizures, diagnosed with sagittal sinus venous thrombosis (SSVT). On recovery she developed blurry vision due to acute posterior multifocal placoid pigment epitheliopathy (APMPPE). APMPPE, an inflammatory chorioretinal disease, presents as visual impairment that precedes accompanying neurological manifestations. The association of APMPPE with SSVT is rare, and APMPPE occurring after SSVT has not been previously reported. Awareness of this possibility might facilitate management of future cases. Our observation suggests a link between APMPPE and SSVT especially among young stroke patients who develop visual symptoms not readily explained by cerebral pathology.

KEYWORDS:

• Sagittal sinus venous thrombosis
• acute posterior multifocal placoid pigment epitheliopathy
• stroke
• inflammation