Lymphoproliferative disorders in the lacrimal caruncle: report of three cases and review of literature

ABSTRACT

This report included three cases of lymphoproliferative disorders developing from the lacrimal caruncle. The first case was an 11-year-old boy with reactive lymphoid hyperplasia in the left lacrimal caruncle. The second case was an 80-year-old woman with reactive lymphoid hyperplasia in the right lacrimal caruncle. The third case was a 77-year-old man with follicular lymphoma in the left lacrimal caruncle. Our literature review of cases with lacrimal caruncular lesions showed 11 reported cases with reactive lymphoid hyperplasia and 17 with malignant lymphoma. There had been no previous report on follicular lymphoma in the lacrimal caruncle.

KEYWORDS:

• Follicular lymphoma
• lacrimal caruncle
• lymphoproliferative disorders
• reactive lymphoid hyperplasia

Authors’ contributions

All authors qualify for authorship based on contributions to the conception and design (YT), acquisition of data (YT), literature search (YT), and analyses and interpretation of data (all authors). All authors contributed to drafting the article and revising it critically for important intellectual content and final approval of the version to be published.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

All data are included in this case report.

Other contributors

The authors wish to thank Dr. Akira Satou at Department of Surgical Pathology, Aichi Medical University Hospital for helping us in interpretation of pathological findings.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.