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British Journal of Neurosurgery Volume 21, 2007 - Issue 6
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Review Article

Advanced MRI in the management of adult gliomas

Mr M. D. Jenkinson Departments of Neurosurgery; Division of Neuroscience, University of Liverpool, LiverpoolCorrespondence[email protected]
,
D. G. Du Plessis Division of Neuroscience, University of Liverpool, Liverpool
,
C. Walker Division of Neuroscience, University of Liverpool, Liverpool; Clatterbridge Cancer Research Trust, JK Douglas Laboratories, Clatterbridge Hospital, Wirral, UK
&
T. S. Smith Neuroradiology, Walton Centre for Neurology and Neurosurgery
Pages 550-561 | Received 14 May 2007, Accepted 21 Aug 2007, Published online: 06 Jul 2009
 
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Abstract

Gliomas are a heterogeneous group that account for ∼86% of primary brain neoplasms, and include astrocytic and oligodendroglial tumours, as well as a variety of less common histopathological subtypes. Magnetic resonance imaging has become the accepted mode of imaging for the clinical management of these tumours. MRI features bear close resemblance to the histopathology grading and prognosis of these tumours. Currently, conventional MRI is used to aid diagnosis, plan neurosurgical approaches, and monitor response to therapy and disease progression. More recent developments in the field of MRI include MR spectroscopy, perfusion MRI, diffusion-weighted imaging, intraoperative MRI and functional MRI. These newer techniques have been adopted with varying success in the management of adult gliomas. This review focuses on the application of advanced MR imaging in the clinical management of adult gliomas.

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