117
Views
22
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

The use of flupirtine in treatment of tinnitus

, &
Pages 93-95 | Published online: 08 Jul 2009
 

Abstract

Conclusion: Flupirtine, a functional NMDA antagonist, does not seem to be efficacious in the treatment of tinnitus. Objectives: The purpose of this study was to investigate whether flupirtine has any beneficial effect on tinnitus perception. Patients and methods: Twenty-four patients were selected (6 female and 18 male patients) with continuous subjective tinnitus. Eight patients suffered left-sided tinnitus, 4 right-sided tinnitus and 12 bilateral tinnitus. We assessed the burden of the tinnitus by loudness visual analogue scale (VAS) and tinnitus questionnaire (TQ) according to Hallam et al., and Hiller and Goebel. All patients were treated with a 2×100 mg daily dosage of oral flupirtine for 3 weeks in an open prospective design. Results: There was no statistical effect on VAS and TQ of the treatment with flupirtine. Only one patient (4.2%) experienced a positive effect on the tinnitus but discontinued the treatment because of amnesia and concentration disorders.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 226.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.