Inflammation of the Posterior Uvea: Findings on Fundus Fluorescein and Indocyanine Green Angiography

Abstract

Purpose: To investigate the additional benefit of indocyanine green angiography (ICGA) over fundus fluorescein angiography (FA) in patients with posterior uveal inflammation. Methods: The features of 19 patients with different forms of posterior uveitis (Vogt-Koyanagi-Harada disease [n = 5], serpiginous choroiditis [n = 5], multifocal choroiditis [n = 5], and sarcoidosis [n = 4]) were analyzed. Results: On ICGA, inflammatory lesions were hypofluorescent in all phases, and early choroidal vessel dilation and leakage was noted near the lesions. Conclusions: The combined use of FA and ICGA helps gauge the severity of inflammation in the choroid and the retina during active inflammation. In quiescent stages, however, ICGA does not give any additional information.

KEYWORDS:

• Fluorescein angiography
• indocyanine green
• Vogt-Koyanagi-Harada disease
• choroiditis
• sarcoidosis