The Pattern of Uveitis in Sri Lanka

ABSTRACT

Purpose: To describe the pattern of uveitis at a tertiary uveitis referral clinic in Sri Lanka.

Methods: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed.

Results: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). 485 (65%) were idiopathic. The top identified causes of AU were seronegative-spondyloarthropathy-related-AU (37, 13%), HLA-B27-related-AU without systemic associations (25, 9%), herpetic-AU (18, 6%), and trematode uveitis (8, 3%). The main posterior uveitis were toxoplasmosis (34, 18%), tuberculosis (21, 11%), and sarcoidosis (17, 9%). 78% of intermediate uveitis were idiopathic, with 12 (8%) tuberculosis, and 10 (7%) sarcoidosis. The most common panuveitis were sarcoidosis (18, 14%), tuberculosis (14, 11%), and Vogt–Koyanagi–Harada disease (10, 8%). Among children (≤12 years) accounting for 25 (3%) of cases, the most common presentations were idiopathic intermediate uveitis (7, 28%), idiopathic-AU (4, 16%), toxoplasmosis (4, 16%), trematode uveitis (3, 12%), and toxocariasis (2, 8%).

Conclusions: An infectious etiology must be considered in posterior uveitis and uveitis among children in the Sri Lankan population.

Keywords:

• Asia
• epidemiology
• infection
• Sri Lanka
• uveitis

DECLARATION OF INTEREST

Financial Disclosure: Jay Siak (None), Mirna Kumaradas (None), Soon-Phaik Chee is a consultant for the following companies and she received travel grants and honorariums from the companies without financial conflicts of interest in relation to this article (Bausch + Lomb Technolas, Hoya Surgical Optics Pte Ltd, Abbott Medical Optics Inc, Alcon Laboratories, Allergan Inc, Santen Pharmaceuticals, Carl Zeiss, AbbVie Ltd). The authors alone are responsible for the content and writing of the article.