Pediatric Inflammatory CNV: A Case Series from a Tertiary Referral Centre

ABSTRACT

Purpose: To report a case series of pediatric inflammatory choroidal neovascularization (CNV) seen at referral uveitis clinic.

Methods: Records of pediatric patients with uveitis and inflammatory CNV between January 2000 and December 2012 were analyzed.

Results: Ten eyes of seven patients were included. Mean age 12.6 years, mean follow-up 89.6 months. Three out of seven patients had bilateral CNV. Subfoveal CNV was noted in five eyes, extrafoveal CNV in three eyes and juxtafoveal and peripapillary CNV each in one eye. All patients received corticosteroids; immunosuppressives were used in three patients. Additional anti-VEGF injections were given, in six eyes, anti-VEGF and PDT in one eye and only PDT in three eyes.

Conclusion: Pediatric inflammatory CNV though challenging, can be successfully managed with prompt therapy of the underlying uveitic disease, coupled with additional local therapy to selectively target the CNV.

Keywords:

• anti-VEGF
• corticosteroids
• immunosuppressives
• PDT
• pediatric CNV

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.