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Ocular Immunology and Inflammation Volume 29, 2021 - Issue 4
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Invited Review

Differential Diagnosis of Vitritis in Adult Patients

Sarah Touhamia Department of Ophthalmology, Reference Center in Rare Diseases, DHU Sight Restore, Hôpital Pitié Salpêtrière, Sorbonne Université, Paris, FranceCorrespondence[email protected]
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,
Mathilde Leclercqa Department of Ophthalmology, Reference Center in Rare Diseases, DHU Sight Restore, Hôpital Pitié Salpêtrière, Sorbonne Université, Paris, FranceView further author information
, MD,
Dinu Stanescu-Segalla Department of Ophthalmology, Reference Center in Rare Diseases, DHU Sight Restore, Hôpital Pitié Salpêtrière, Sorbonne Université, Paris, France;b Centre Nord Exploration Ophtalmologique, Lille, FranceView further author information
, MD, PhD,
Valérie Touitoua Department of Ophthalmology, Reference Center in Rare Diseases, DHU Sight Restore, Hôpital Pitié Salpêtrière, Sorbonne Université, Paris, FranceView further author information
, MD, PhD &
Bahram Bodaghia Department of Ophthalmology, Reference Center in Rare Diseases, DHU Sight Restore, Hôpital Pitié Salpêtrière, Sorbonne Université, Paris, FranceORCID Iconhttps://orcid.org/0000-0002-0962-5301View further author information
, MD, PhDORCID Icon
Pages 786-795 | Received 14 Dec 2020, Accepted 26 Feb 2021, Published online: 18 May 2021
 
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ABSTRACT

The term “vitritis” refers to the presence of a cellular infiltration of the vitreous body, usually in the context of an intraocular inflammation, but not exclusively. Intermediate uveitis is the most prominent cause of vitritis, including infectious and auto-immune/auto-inflammatory etiologies. Corticosteroids and immunosuppressive therapies should not be started before ruling out the infectious causes of vitritis, especially in immunosuppressed individuals. Other situations can mimic intermediate uveitis such as amyloidosis and ocular tumors. Primary intraocular lymphoma should always be suspected in case of vitreous infiltrations in individuals aged over 50 years.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Additional information

Funding

The authors have no funding to report.

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