Acute Idiopathic Maculopathy Following SARS-CoV-2 Vaccination

ABSTRACT

A 49-year-old man presented with acute unilateral blurred vision one week after SARS-CoV-2 vaccination. A unilateral serous detachment of the macula, intraretinal hemorrhages, vitritis, and anterior chamber cell was found. Diagnostic testing was negative for infectious and inflammatory causes, and a diagnosis of acute idiopathic maculopathy (AIM) was made. Symptoms and serous detachment resolved over 12 weeks, with residual retinal pigment epithelial changes consistent with the disease course. AIM is a rare diagnosis that presented in close proximity to SARS-CoV-2 vaccination without evidence of coxsackievirus infection. Further research is necessary to clarify an association between this vaccine and uveitis.

KEYWORDS:

• COVID
• maculopathy
• SARS-CoV-2
• uveitis
• vaccine

Data availability statement

All data generated or analyzed during this study are included in this article and its supplementary material files. Further enquiries can be directed to the corresponding author.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Statement of ethics

This research was conducted ethically in accordance with the World Medical Association Declaration of Helsinki. Ethics approval was not required to conduct this retrospective case report. The subject of this case report provided written informed consent to publish this case and the accompanying images.

Additional information

Funding

The author(s) reported that there is no funding associated with the work featured in this article.