Advanced search
Publication Cover
Biological Rhythm Research Volume 42, 2011 - Issue 2
Submit an article Journal homepage
90
Views
2
CrossRef citations to date
0
Altmetric
Articles

Opposing circadian rhythms of CD3+, CD4+ and CD3+, CD8+ lymphocyte subpopulations in healthy humans

Gianluigi Mazzoccoli Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), ItalyCorrespondence[email protected]
,
Angelo De Cata Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
,
Antonio Greco Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
,
Marcello Damato Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
,
Davide Gennaro De Pinto Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
,
Marcella Montrano Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
,
Nunzia Marzulli Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
,
Mariangela Pia Dagostino Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
&
Stefano Carughi Department of Internal Medicine, Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG), Italy
 show all
Pages 111-118 | Received 08 Feb 2010, Accepted 18 Feb 2010, Published online: 07 Jul 2010
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

Lymphocyte subpopulations present circadian variation of some of their subsets and this variation may influence the magnitude and expression of immune responses. The aim of this study was to analyze the dynamics of variation of specific lymphocyte subsets. Lymphocyte subpopulation analyses were performed on blood samples collected every four hours for 24 hours from 15 healthy subjects aged 37–54 years. A clear circadian rhythm was validated for CD8 with acrophase at noon and for CD3 and CD4 with acrophase at night. Specific lymphocyte subsets present different profiles of nyctohemeral changes and this might explain time-related variations of immune responses.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 387.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.