ABSTRACT
The relationship between air pollution exposure and haematology remains controversial. Evidences in the effect of trace organic air pollutants and in the impact of such exposure on lipid and protein levels are scarce. This work investigated the health effects of medium-term exposure to traffic-related air pollution on both haematological and biochemical indices in animal models. Two groups of albino mice (Mus musculus) were exposed to ambient air polluted by vehicle exhaust for three and six months, and one group was kept as control. Results found significant depletions (p < 0.05) in red blood cells, packed cell volume, neutrophils, eosinophils, monocytes, and total cholesterol after air pollution exposure. On the contrary, significant elevations (p < 0.05) were observed in platelet, lymphocytes, and serum albumin compared to control condition. Correlation data suggested that significant changes in blood parameters may be altered by the synergistic effect of several organic and inorganic air pollutants.
Acknowledgments
Author AKF gratefully thanks the Indian Council for Cultural Relations (ICCR) for providing scholarship to carry out Ph.D. research programme in India. All authors are thankful to the Yale Tropical Research Institute, USA and Ravi Diagnostic Laboratory, Mysore for instrumentation and laboratory analyses; and to the Department of Zoology, University of Mysore for providing laboratory animals. We also acknowledge the helps, assistances, and facilitations of our colleagues Sreenivasa, Chandana M., and Amruta Nori-Sarma in the sampling and collection of data during field work.
Disclosure statement
The authors have no competing financial interests.
Supplementary Material
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