The association between gender difference with metabolic syndrome, metabolic syndrome score and serum vitamin D levels in Korean adults

Abstract

This study assessed the association between gender difference with metabolic syndrome (MetS), metabolic syndrome score (MSS) and serum vitamin D levels in Korean adults. Analyses were restricted to 5147 adults (2162 men; 2985 women) aged 20 and older, using the 2012 Korean National Health and Nutrition Examination Survey (KNHANES) data. In the non-adjusted model, serum 25-hydroxyvitamin D [25(OH)D] levels were inversely associated with MetS (p = .001) and MSS (p = .009) in men, but positively associated with MetS (p = .002) and MSS (p < .001) in women. However, when adjusted for related variables (including age), serum 25(OH)D levels were inversely associated with MetS (p < .001) and MSS (p < .001) in men, but were not associated with MetS (p = .200) and MSS (p = .541) in women. In conclusion, increases in MetS and its components were inversely associated with the serum vitamin D concentration in men.

Keyword:

• Gender difference
• metabolic syndrome score
• metabolic syndrome
• vitamin D

Disclosure statement

The authors declare that there is no conflict of interest associated with this manuscript. All authors were involved in the concept and design of this study. HY, DKJ, and CEP collected the data and performed the analyses. HY, HJO, and SGK assessed the quality of study design and the data independently. HY performed the statistical analysis and wrote the manuscript.