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Food composition and analysis

Platelet hyperactivity: a comparison of water-soluble, bioactive compound levels in commercial tomato products and water-soluble tomato concentrate, a supplement with an approved EFSA antiplatelet health effect

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Pages 31-44 | Received 07 Jul 2022, Accepted 10 Oct 2023, Published online: 23 Oct 2023
 

Abstract

The aim of this study was to evaluate and compare the concentration of water-soluble bioactive compounds in tomato products (polyphenols profile, water-soluble vitamins and nucleophilic substances) with the concentration of the same bioactive molecules existing in a water-soluble patented tomato extract, water-soluble tomato extract (WSTC), commercially available as FruitFlow®. This patented tomato extract has been recognised by EFSA (European Food Safety Authority) in a specific Health Claim declaration as having an “Antiplatelet health effect”. More than 100 commercial tomato samples, coming from 18 different processing tomato companies worldwide, were analysed and compared with the FruitFlow® supplement. According to the multivariate statistical analyses applied to the data matrix, it is possible to conclude that the commercial tomato products measured (pastes, purees, others) show a significantly higher concentration of water-soluble bioactive molecules (nucleosides/nucleotides and polyphenols) responsible for an anti-platelet aggregation effect than the FruitFlow® dietary supplement.

Acknowledgements

The authors are grateful to all the Tomato Foundation partnership, in particular to the 18 worldwide tomato companies that have supported this study.

Author contributions

L.S., D.S. and J.H. designed and conceived the research. E.C., C.S., R.V., F.D.S, M.T.R. provided the experimental data on bioactive substances, E.C. and C.S. performed the statistical analyses, L.S., A.M.B., D.S. and J.H. edited the manuscript.

Conflicts of interest

We declare that there are no conflicts of interest.

Additional information

Funding

The Tomato Foundation and SSICA supported this work.

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