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Journal of Asian Natural Products Research Volume 18, 2016 - Issue 7
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Articles

Two new lignans from the aerial part of Vitex negundo

Xiu-Fang NieKey Laboratory of Structure-Based Drug Design & Discovery, Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Li-Li YuKey Laboratory of Structure-Based Drug Design & Discovery, Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Yuan TaoKey Laboratory of Structure-Based Drug Design & Discovery, Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Jian HuangKey Laboratory of Structure-Based Drug Design & Discovery, Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
,
Li-Qin DingTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
,
Xin-Chi FengTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
,
Miao-Miao JiangTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
,
Lin ZhengTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
,
Li-Xia ChenKey Laboratory of Structure-Based Drug Design & Discovery, Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, ChinaCorrespondence[email protected] [email protected]
&
Feng QiuTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, ChinaCorrespondence[email protected] [email protected]
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Pages 656-661 | Received 09 Sep 2015, Accepted 13 Jan 2016, Published online: 21 Mar 2016
 
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Abstract

A new phenyldihydronaphthalene-type lignan, (3R,4S)-6-hydroxy-4-(4-hydroxy- 3-methoxyphenyl)-5,7-dimethoxy-3,4-dihydro-2-naphthaldehyde-3a-O-β-d-glucopyranoside (1), and a new phenylnaphthalene-type lignan, 6,7,4′-trihydroxy-3′-methoxy-2,3- cycloligna-1,4-dien-2a,3a-olide (2), along with 10-known lignan derivatives (3–12) were isolated from the aerial part of Vitex negundo var. heterophylla. Their structures were established by comprehensive 1D- and 2D-NMR spectroscopic analyses.

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